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Alvaro Olivera-Nappa


Alvaro Olivera-Nappa

University of Chile, Chile

Biography

Alvaro Olivera-Nappa has received a PhD in Chemical Engineering, specializing in Biotechnology and Protein Engineering. He was a Post-doctoral Fellow in Santiago, Chile, and Delft, The Netherlands, and has occupied a Visiting Scholar position at the Department of Biochemistry of the University of Cambridge, UK, under Professor Sir Tom Blundell. Since 2013, he is an Assistant Professor at the University of Chile. He has published articles in the fields of protein science, protein engineering, mathematical modeling of biological systems and the prediction of the effect of mutations in cancer and disease. He has developed mathematical, statistical and computational tools to understand and design protein function from a molecular and relational point of view, to represent and analyze complex chemical and biological processes and to design and implement biotechnological solutions and applications. He is interested in biotechnology applications for economic development and constantly promotes innovation and science education as drivers of social development.

Abstract

Abstract : VHL-Hunter: A predictor of the impact of missense mutations in the function of the Von Hippel-Lindau protein (pVHL), risk of clear cell renal carcinoma and severity of pVHL-associated diseases