Bioinformatics

Biography

Judit Ovádi has expertise in Biochemistry, Enzymology and Molecular Biology. She defined the metabolic channeling at microscopic and macroscopic levels as a powerful mechanism to control and direct metabolic pathway at crossroads. Her research team showed the sensing potency of the microtubule network at system level that can regulate signaling pathways due to its decoration by interacting partners. They discovered a unique brain-specific protein denoted Tubulin Polymerization Promoting Protein (TPPP/p25) that displays two exciting characteristics: intrinsically unstructured and enriched in brain inclusion in the case of Parkinson disease and other synucleinopathies. The structural and functional features of this protein have been characterized at different levels of organizations under physiological and pathological conditions. She has supervised several DSc and PhD dissertations. She was an invited Visiting Professor in USA, Spain and Italy; Invited Speaker in international congresses in the last few years in Tokyo, San Francisco, Jerusalem, Orleans, Nice. At present, she is a Professor Emerita, Laureata Academiae of the Research Center of Hungarian Academy of Sciences.

Abstract

Abstract : Challenging drug target for moonlighting and chameleon proteins